(3-Aminobenzyl)carbamic acid tert-butyl ester

(3-Aminobenzyl)carbamic acid tert-butyl ester - Names and Identifiers

Name	tert-Butyl 3-aminobenzylcarbamate
Synonyms	tert-Butyl 3-aminobenzylcarbamate tert-Butyl-(3-aminobenzyl)carbamat tert-Butyl (3-aminobenzyl)carbamate 3-(Aminomethyl)aniline, 3-BOC protected 3-Amino-N-(tert-butoxycarbonyl)benzylamine tert-Butyl 3-aminobenzylcarbamate AldrichCPR tert-butyl N-[(3-aMinophenyl)Methyl]carbaMate (3-Aminobenzyl)carbamic acid tert-butyl ester N-(3-aMinophenylMethyl)carbaMic acid t-butyl ester carbamic acid, N-[(3-aminophenyl)methyl]-, 1,1-dimethylethyl ester tert-Butyl (3-aminobenzyl)carbamate, 3-{[(tert-Butoxycarbonyl)amino]methyl}aniline
CAS	147291-66-5
EINECS	200-110-4
InChI	InChI=1/C12H18N2O2/c1-12(2,3)16-11(15)14-8-9-5-4-6-10(13)7-9/h4-7H,8,13H2,1-3H3,(H,14,15)

(3-Aminobenzyl)carbamic acid tert-butyl ester - Physico-chemical Properties

Molecular Formula	C12H18N2O2
Molar Mass	222.28
Density	1.095±0.06 g/cm3(Predicted)
Melting Point	48.0 to 56.0 °C
Boling Point	386.0±25.0 °C(Predicted)
Flash Point	187.263°C
Solubility	soluble in Methanol
Vapor Presure	0mmHg at 25°C
Appearance	powder to crystal
Color	White to Light yellow
pKa	12.31±0.46(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.542

(3-Aminobenzyl)carbamic acid tert-butyl ester - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
WGK Germany	3

(3-Aminobenzyl)carbamic acid tert-butyl ester - Introduction

tert-Butyl 3-aminobenzylcarbamate, chemical formula C11H16N2O2, is an organic compound. The following is a description of the nature, use, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or light yellow liquid
-Solubility: Soluble in organic solvents such as ethanol and ether
-Melting point: about 20 ° C
-relative molecular mass: 208.26g/mol

Use:
- tert-Butyl 3-aminobenzylcarbamate is commonly used as an intermediate in organic synthesis and can be used to prepare compounds such as amino acids, drugs and dyes.
-The compound can also be used as a chemical analysis reagent, and has certain application value in the field of pharmaceutical research and biochemistry.

Method:
- tert-Butyl 3-aminobenzylcarbamate has many preparation methods. The commonly used method is to react benzylamine with tert-butyl cyanoformate in the presence of sodium carbonate. The reaction conditions are generally carried out at room temperature.

Safety Information:
- tert-Butyl 3-aminobenzylcarbamate is an organic compound and should be exposed to personal protective measures, such as wearing laboratory gloves.
-This compound may be irritating to the eyes and skin, and has potential allergic effects, so avoid direct contact when using.
-During operation, care should be taken to avoid inhaling its vapor or mist, because its vapor may cause irritation to the respiratory tract.
-need to be stored in a cool, dry place, and avoid contact with oxidants, strong acids and other substances to avoid dangerous reactions or fire.
-When using and handling this compound, follow relevant safety procedures and pay attention to effective ventilation.

Last Update：2024-04-09 20:49:11